The MediHerb Podcast

As GLP-1 medications become increasingly integrated into weight management, understanding their implications for muscle and bone health is essential for practitioners supporting patients through significant weight loss. In this episode, Laurence Katsaras is joined by Professor David Scott, exercise scientist and NHMRC Emerging Leadership Fellow at Deakin University, to explore the latest research on GLP-1 therapies and body composition. They discuss the relationship between weight loss and lean mass reduction, the distinction between muscle loss and changes in muscle composition, and the potential implications for long-term physical function, bone health and fracture risk.

David shares practical, evidence-informed strategies to help practitioners support healthy body composition throughout the weight loss journey. From protein requirements and nutritional considerations to the importance of progressive resistance training, he outlines how specialised exercise prescription can help minimise muscle and bone loss. The conversation also explores accessible clinical tools for monitoring body composition and physical function, strategies for supporting sustainable behaviour change, and the opportunities for practitioners to provide individualised lifestyle support. Discover how integrating targeted nutrition, exercise and ongoing monitoring can help patients achieve healthier, more sustainable outcomes while using GLP-1 therapies.

Head over to David's 2025 article - Exercise and dietary recommendations to preserve musculoskeletal health during weight loss in adults with obesity: A practical guide

https://link.springer.com/article/10.1007/s11154-025-09968-3

Globe artichoke has a long history in Western herbal medicine, yet its broad applications can be easy to overlook in an era of increasingly targeted therapeutic approaches. In this episode, we welcome David Casteleijn back to the MediHerb Podcast to explore why this classic herb deserves renewed attention. David shares his clinical experience using globe artichoke as a general digestive tonic, supporting digestive function, while considering its bitter principles, choleretic and cholagogue actions, and prebiotic fructans.

The conversation takes a deeper look at where globe artichoke may fit in contemporary naturopathic practice, including digestive dysfunction associated with nervous system dysregulation and the complex relationship between the gut, microbiome and nervous system. David also discusses the apparent contradiction of using a fructan-containing herb in people with IBS, challenging an overly symptom-focused approach to FODMAPs and highlighting the importance of considering the whole person. With insights from his observational research into herbal medicine use in anxiety and depression, this episode offers a fresh clinical perspective on a versatile herb that deserves a place in your dispensary.

How can practitioners help patients achieve lasting success with GLP-1 medications beyond weight loss alone? Glenn Mackintosh shares his expertise on psychology, behaviour change strategies and interdisciplinary care that turn short-term results into sustainable outcomes.

 

Bio: Glenn is a psychologist who is extremely passionate about eating, physical activity, weight, and body image. He is the Clinical Director of the Weight Management Psychology Clinic, the Creator of the Transformation Support Community Online Program, and the Author of the bestselling 'Thinsanity: 7 Steps to Transform Your Mindset & Say Goodbye to Dieting Forever'. He enjoys supporting the health-conscious public and training the wonderful health professionals who support them.

 

Links:

• The Missing Piece Free eBook:

https://www.weightmanagementpsychology.com.au/the-missing-piece-ebook/   

• Weight Management Psychology Clinic:

https://www.weightmanagementpsychology.com.au/ 

• Transformation Support Community Online Program:

https://programs.glennmackintosh.com/transformation-support-community

• 'Who Do You Want to Be?' Blog:

https://www.weightmanagementpsychology.com.au/who-do-you-want-to-be-in-2023-personal-reflection-free-resource/

GLP-1 medications are reshaping the management of obesity and metabolic health, but where do integrative practitioners fit into this rapidly evolving landscape? In this episode, Laurence Katsaras speaks with internationally recognised obesity and metabolic health expert Dr Jacqueline Jacques about GLP-1 therapies, why obesity should be viewed as a chronic disease, and the opportunities for naturopathic and functional medicine practitioners to support patients throughout their treatment journey.
The discussion explores the often-overlooked challenges of GLP-1 therapy, including nutrient deficiencies, lean muscle and bone loss, side effect management, and the sobering reality of post-treatment weight regain - what it means clinically, highlighting the post-cessation window as a genuine opportunity for integrative practitioners. Jacqueline introduces the concept of the "life cycle of care," encouraging practitioners to move beyond seeing integrative medicine as an alternative and instead position themselves as collaborative partners alongside pharmacotherapy.

In this episode of the MediHerb podcast, Laurence Katsaras is joined by Dr Antony Underwood, integrative paediatrician and cofounder of Spectrumceuticals, to explore the rapidly evolving science of probiotics and microbiome therapy. Together, they unpack strain specificity, probiotic research quality, taxonomy and trademarks, storage and stability, and how practitioners can apply evidence-based probiotic prescribing in clinical practice.

The conversation also dives into probiotics in paediatric care and the first 1000 days, including applications for NEC prevention, colic, reflux, antibiotic-associated diarrhoea and immune resilience. Dr Underwood also shares insights into diet, polyphenols, fermented foods, postbiotics and emerging “keystone” bacteria shaping the future of personalised microbiome medicine.

In this clinically rich conversation, David Casteleijn revisits Passionflower through a far more nuanced lens than its traditional “mild anxiolytic” label. Drawing on decades of practice and deeply personal clinical observations, David explores the herb’s powerful role in acute nervous system dysregulation—particularly in states of panic, PTSD, and heightened sympathetic activation. He shares practical insights into “stacked” dosing strategies, demonstrating how passionflower can rapidly interrupt escalation cycles without the residual sedation, making it a valuable tool both in-clinic and for patient self-management.

Beyond acute use, this episode expands the conversation into long-term nervous system retraining, highlighting passionflower’s potential role in supporting neuroplasticity and reducing reliance on substances such as alcohol and anxiolytics. David also challenges common assumptions around dependency, safety, and herb-drug interactions, while unpacking emerging insights into its broader neurotransmitter activity. With discussion spanning ADHD, addiction patterns, and herb selection, this episode offers practitioners a deeper, more flexible framework for prescribing Passionflower across a wide spectrum of presentations.

In this episode of the MediHerb Podcast, we welcome Angela Hywood to draw on some unanswered questions from the MediHerb Unplugged livestream. Angela shares her evidence-informed approaches to supporting patients in complex clinical scenarios, with dosing strategies and clinical rationale.

 

Bio: Angela Hywood is an experienced naturopathic clinician with over 26 years of clinical experience, specialising in integrative endocrinology, women’s health, fertility and pregnancy care. Angela is a well-known speaker at complementary and integrative medicine conferences in both Australia and internationally and has published articles in complementary medicine journals in Australia and USA.

Concussion is often minimised as a “head knock,” yet it represents a complex traumatic brain injury with far-reaching systemic consequences. In this episode, we welcome Louise Cork to unpack the physiological cascade that unfolds following impact — from axonal shearing and ionic shifts to glutamate excitotoxicity, blood-brain barrier disruption, neuroinflammation, and gut permeability. We explore how this acute response can evolve into persistent post-concussion syndrome (PCS), and why some patients remain symptomatic months, or even years, after the initial injury.

Through a functional naturopathic lens, this conversation provides practical guidance on assessment, red flags, collaborative care, and therapeutic layering, while discussing the critical role of the gut-brain axis, immune activation, metabolic dysfunction, glial priming, autonomic dysregulation, and mitochondrial compromise. With the right support — nutrients, targeted herbal medicine, and realistic lifestyle rehabilitation, post-concussion outcomes are not fixed, and meaningful recovery is possible.